Extended Data Fig. 2: Spatial distribution of microglia and L2/3 IT neurons in the SEA-AD dataset. | Nature Machine Intelligence

Extended Data Fig. 2: Spatial distribution of microglia and L2/3 IT neurons in the SEA-AD dataset.

From: Inferring spatial single-cell-level interactions through interpreting cell state and niche correlations learned by self-supervised graph transformer

Extended Data Fig. 2: Spatial distribution of microglia and L2/3 IT neurons in the SEA-AD dataset.

a, The strength of interactions influencing the expression of RORB. b, Spatial distribution of microglia subgroups and excitatory neurons. Specifically, microglia subgroup 1 is located in layers 2 and 3, subgroup 2 in layers 4 and 5, and subgroup 3 in layer 6. c, Super type annotation of L2/3 IT neurons in Gabitto et al. d, UMAP visualization of slides using the inferred network strength as features, with colour indicating slide from patients with or without dementia.

Back to article page