Immunotherapy has changed the treatment paradigm for patients with cancer, but patient selection, response assessment and treatment duration require further refinement. A recent study reports that the kinetics of circulating tumor DNA reflect response and resistance to immunotherapy treatment across multiple cancer types and could be used to tailor treatment.
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Tie, J. Tailoring immunotherapy with liquid biopsy. Nat Cancer 1, 857–859 (2020). https://doi.org/10.1038/s43018-020-00113-4
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DOI: https://doi.org/10.1038/s43018-020-00113-4
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Dynamics of tumor in situ fluid circulating tumor DNA in recurrent glioblastomas forecasts treatment efficacy of immune checkpoint blockade coupled with low-dose bevacizumab
Journal of Cancer Research and Clinical Oncology (2024)
