Extended Data Fig. 4: Kaplan–Meier curves of event-free, overall survival (EFS and OS) and recurrence-free survival (RFS) stratified by different pathologic responses to neoadjuvant treatment.
a, b, c, Patients with (n = 14) or without pDS (n = 43). The cutoff of landmark analysis was 6 months for EFS and OS, and 3 months for RFS. Hazard ratio (HR) was calculated by comparing patients with vs without pDS. d, e, f, Patients with pCR (n = 29), paR (n = 14) and non-pDS (n = 14). CI, confidence interval; ns: non-significant; paR, partial response, Tis/Ta/T1N0M0; pCR, pathologic complete response; pDS, pathologic downstaging. p-values were calculated by using two-sided log-rank test.
