Extended Data Fig. 4: Vaccine peptide hydrophobicity and immunogenicity.
From: Atezolizumab plus personalized neoantigen vaccination in urothelial cancer: a phase 1 trial
Each vaccine peptide is represented in this figure by the maximum GRAVY score observed within any contiguous stretch of 7 amino acids. The plot depicts the mean with standard error of the mean. N = 48 for non-responsive peptides, N = 39 for responsive peptides. Statistical significance was determined by the two-tailed unpaired t-test. P = 0.0076.
