Extended Data Fig. 5: Evolution of the TME through treatment.
a Summary of features that changed between baseline and on-nivo samples across all patients b Ratio of Cancer cells to T cells in stroma border at baseline and on-nivo timepoint across all patients c Proportion of all CD45RO+ cells at baseline and on-nivo timepoint across all patients d Diversity of cells surrounding Mac_Other cells at baseline and on-nivo timepoint across all patients e Summary of features that changed between baseline and on-nivo samples across paired samples(3.5) f Ratio of Cancer cells to T cells in stroma border at baseline and on-nivo timepoint across paired samples g Ratio of Cancer cells to unclassified cells in stroma border at baseline and on-nivo timepoint across paired samples h Ratio of NK cells to T cells at baseline and on-nivo timepoint across paired samples For panels b-d and f-h, N = 101 patients.
