Extended Data Fig. 6: Survival analysis stratified by RAS mutation status and primary tumor sidedness within the CRC cohort. | Nature Cancer

Extended Data Fig. 6: Survival analysis stratified by RAS mutation status and primary tumor sidedness within the CRC cohort.

From: Hypoxia-responsive CEA-targeted CAR T cells in CEA-positive solid tumors through intraperitoneal or intravenous infusion: a phase 1 trial

Extended Data Fig. 6: Survival analysis stratified by RAS mutation status and primary tumor sidedness within the CRC cohort.

Kaplan-Meier curves for PFS and OS stratified by RAS mutation status (mutant vs. wild-type) in the I.P. (a-b) group and I.V. (e-f) group within the CRC cohort. Kaplan-Meier curves for PFS and OS stratified by primary tumor sidedness (left vs. right) in the I.P. (c-d) and I.V. (g-h) groups within the CRC cohort. Between-group survival differences were compared using the log-rank test. For comparisons where Kaplan-Meier curves crossed (indicating non-proportional hazards), the Breslow and Tarone-Ware tests were additionally applied. Abbreviations: CRC, colorectal cancer; I.P., intraperitoneal infusion; I.V., intravenous infusion; PFS, progression-free survival; OS, overall survival; NR, not reached.

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