Extended Data Fig. 2: Serum biomarker fold change in relation to CRS occurrence.
Correlation between post-infusion (a) IL-6 and (b) CRP fold change and CRS occurrence in the I.P. and I.V. groups. In each boxplot, the central line represents the median, the box edges represent the interquartile range (IQR, 25th–75th percentile), and the whiskers extend to 1.5 × IQR. Statistical comparisons were performed using two‑sided Wilcoxon rank‑sum tests; no adjustment for multiple comparisons was applied. Abbreviations: CRS, cytokine release syndrome; I.P., intraperitoneal infusion; I.V., intravenous infusion; CRP, C-reactive protein; DL1, dose level 1; DL2, dose level 2; DL3, dose level 3; DL4, dose level 4.
