Table 1 Mendelian randomization estimates for the association between lifespan-related traits and risk of COVID-19.
From: Genetic and phenotypic analysis of the causal relationship between aging and COVID-19
Exposure | Outcome | OR | 95% CI | P |
|---|---|---|---|---|
Healthy aging | HGI covid susceptibility | 0.33 | 0.13−0.85 | 2.2e−02 |
Healthy aging | HGI hosp covid vs. nonhosp | 0.38 | 0.18−0.78 | 9.1e−03 |
Healthy aging | UKBB covid vs. neg | 0.25 | 0.09−0.69 | 7.0e−03 |
Healthy aging | UKBB covid vs. pop | 0.12 | 0.05−0.32 | 1.6e−05 |
Longevity | HGI covid susceptibility | 0.68 | 0.56−0.82 | 8.5e−05 |
Longevity | HGI hosp covid vs. nonhosp | 0.81 | 0.71−0.93 | 2.3e−03 |
Longevity | HGI hosp covid vs. pop | 0.89 | 0.82−0.96 | 2.9e−03 |
Longevity | UKBB covid vs. neg | 0.58 | 0.47−0.72 | 5.1e−07 |
Longevity | UKBB covid vs. pop | 0.53 | 0.43−0.65 | 2.3e−09 |
Lifespan | HGI covid susceptibility | 0.45 | 0.27−0.77 | 3.2e−03 |
Lifespan | HGI hosp covid vs. nonhosp | 0.46 | 0.3−0.71 | 3.3e−04 |
Lifespan | HGI hosp covid vs. pop | 0.71 | 0.55−0.91 | 6.8e−03 |
Lifespan | UKBB covid vs. neg | 0.44 | 0.26−0.77 | 3.6e−03 |
Lifespan | UKBB covid vs. pop | 0.31 | 0.18−0.52 | 9.7e−06 |
