Fig. 2: Univariate feature selection.

GSP features with uncorrected p-value < 0.05 and corresponding F-values obtained by linear regression based univariate feature selection for a HC cohort and d ExPro cohort. Higher F-value corresponds to a more significant linear association between GSP feature and serum NfL. Features with corrected p-value < 0.05 after FDR correction for multiple tests are marked with asterisks (*). Panels b, c plot the F-values for the low and high graph frequency features on a template cortical surface for HC cohort. Panels e, f plot the F-values for the low and high graph frequency features on a template cortical surface for ExPro cohort.