Fig. 5: Immune transcriptome induced upon BNT162b2 vaccination. | Communications Medicine

Fig. 5: Immune transcriptome induced upon BNT162b2 vaccination.

From: BNT162b2 vaccination enhances interferon-JAK-STAT-regulated antiviral programs in COVID-19 patients infected with the SARS-CoV-2 Beta variant

Fig. 5

a Genes expressed at significantly higher levels at Day 7–10 from the vaccination were significantly enriched in Hallmark Gene Sets (FDR q value < 0.005). b Relative mRNA levels of 17 genes that are induced at Day 7–10 as compared to Day 0 and enriched in IFN signaling are presented by bar graphs. A p value by the Wald statistic from DESeq2 were listed in Supplementary Data 5. *p < 0.05, ***p < 0.0001, ****p < 0.00001. c Transcriptional signatures in vaccinated naïve individuals and vaccinated COVID-19 patients. The Venn diagram displays the number of significantly induced genes.

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