Table 1 Demographics of 202 pregnant women who underwent 274 prenatal MRI studies.

From: Maternal psychological distress during the COVID-19 pandemic and structural changes of the human fetal brain

N [%] or Median [IQR]

All Subjects

Pre-pandemic

Pandemic

p

Number of subjects

202

137

65

 

 Female fetus

91 [48]

58 [45]

33 [54]

0.22

 Male fetus

100 [52]

72 [55]

28 [46]

 

 With 1 scan

130 [64]

92 [67]

38 [58]

0.23

 With 2 scans

72 [36]

45 [33]

27 [42]

 

Number of MR scans

274

182

92

 

 Time point 1

147 [54]

101 [55]

46 [50]

0.39

 Time point 2

127 [46]

81 [45]

46 [50]

 

GA at MRI

30.4

30.2

30.8

0.15

 

[26.1, 35.3]

[27.0, 35.9]

[25.3, 34.1]

 

Maternal age (years)*

34.1

34.0

34.6

0.63

 

[31.0, 36.9]

[31.0, 37.8]

[30.5, 36.1]

 

Maternal parity (primiparous/multiparous)

109/80

73/55

36/25

0.80

GA at birth (weeks)

39.6

39.7

39.4

0.51

 

[38.7, 40.4]

[38.4, 40.6]

[38.9, 40.1]

 

Birth weight (kg)§

3355

3382

3285

0.91

 

[3078, 3677]

[3079, 3670]

[3064, 3690]

 

Birth head circumference (cm)#

34.3

34.0

34.5

0.19

 

[33.5, 35.5]

[33.0, 35.0]

[33.7, 35.6]

 

Apgar score at 1 min††

8

8

8

0.66

 

[8, 9]

[8, 9]

[8, 9]

 

Apgar score at 5 min‡‡

9

9

9

0.32

 

[9, 9]

[9, 9]

[9, 9]

 

Delivery Mode§§

   

0.10

 Vaginal

101 [68]

59 [62]

42 [78]

 

 Elective C-section

26 [17]

18 [19]

8 [15]

 

 Emergency C-section

22 [15]

18 [19]

4 [7]

 

Race/Ethnicity##

   

0.07

 White

100 [57]

68 [56]

32 [58]

 

 Black

33 [19]

25 [21]

8 [15]

 

 Hispanic or Latino

20 [11]

12 [10]

8 [15]

 

 Asian or Pacific Islander

10 [6]

4 [3]

6 [11]

 

 Others

13 [7]

12 [10]

1 [2]

 
  1. N = 274 MR scans for volumetric data, and N = 204 MR scans for cortical features. GA Gestational age. IQR Interquartile range. *: Based on 200 (99%) subjects. †: Based on 189 (94%) subjects. ‡: Based on 165 (82%) subjects. §: Based on 156 (77%) subjects. #: Based on 108 (53%) subjects. ††: Based on 146 (72%) subjects. ‡‡: Based on 146 (72%) subjects. §§: Based on 149 (74%) subjects. ##: Based on 176 (87%) subjects.