Fig. 2: Minimum spanning tree of whole genome multilocus sequence typing results of 66 E. coli isolates.

Circles/squares/stars represent one isolate, which is connected to the closest relative. The circles represent colistin-susceptible isolates, the squares colistin-resistant isolates and the stars colistin-resistant isolates with mcr genes. The length of the lines in between the isolates is proportional to the allelic distance. Groups of isolates with the same classical MLST sequence type are indicated in the figure, e.g. ST131. The colours represent the different participating medical microbiology laboratories. A cluster was defined as ≥2 isolates with an allelic difference of ≤25. There were no clusters observed for E. coli. Source data: Supplementary Data files 2 and 3 and the Sequence Read Archive of the National Centre for Biotechnology Information (BioProject ID PRJNA754858).