Table 2 Multiple linear association analysis between mtDNA-CN and weight loss at week 24.
From: Higher mitochondrial DNA copy number is associated with metformin-induced weight loss
Characteristics | Metformin arm | Acarbose arm | ||
|---|---|---|---|---|
Beta (95% CI) | P value | Beta (95% CI) | P value | |
Standardized mtDNA-CN | 0.43 (0.13–0.73) | 0.006 | −0.13 (−0.51–0.25) | 0.502 |
Female | 0.75 (0–1.5) | 0.050 | 1.65 (0.69–2.61) | 0.001 |
Age | 0.03 (0–0.07) | 0.048 | 0.05 (0–0.09) | 0.044 |
Baseline weight | 0.05 (0.02–0.09) | 0.005 | 0.11 (0.06–0.15) | <0.001 |