Fig. 7: Estimation of diagnostic accuracy for disease severity prediction. | Communications Medicine

Fig. 7: Estimation of diagnostic accuracy for disease severity prediction.

From: Discovery and systematic assessment of early biomarkers that predict progression to severe COVID-19 disease

Fig. 7

For the individual protein biomarkers S100A8/A9 and CRP, ROC curves of ELISA data as well as coherent multiplex antibody array data were aligned. Marker combinations of 2–4 proteins were selected from linSVM models, which outperform the individual biomarker candidates and exhibit a high accuracy with an AUC of up to 0.928. Area under the ROC curve (AUC) is presented for each biomarker or combination.

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