Table 3 Specificities at given sensitivities for selected individual biomarkers and biomarker combinations.
Biomarker/Biomarker Combination | AUC | Specificity at a Sensitivity of | |||
|---|---|---|---|---|---|
95% | 90% | 85% | 80% | ||
S100A8/A9 | 0.827 | 19.1% | 48.9% | 74.5% | 76.6% |
CRP | 0.837 | 34.0% | 59.6% | 70.2% | 76.6% |
S100A8/A9 + CRP | 0.830 | 46.8% | 46.8% | 74.5% | 76.6% |
S100A8/A9 + TSP1 | 0.872 | 70.2% | 78.7% | 78.7% | 80.9% |
S100A8/A9 + TSP1 + IFNL1 | 0.913 | 80.9% | 80.9% | 83.0% | 83.0% |
S100A8/A9 + TSP1 + ERBB2 | 0.898 | 74.5% | 78.7% | 85.1% | 85.1% |
S100A8/A9 + TSP1 + FINC + IFNL1 | 0.928 | 63.8% | 83.0% | 87.2% | 87.2% |
