Fig. 2: The summary of identification and quantification for all 82 patients. | Communications Medicine

Fig. 2: The summary of identification and quantification for all 82 patients.

From: Quantitative proteomics and phosphoproteomics of urinary extracellular vesicles define putative diagnostic biosignatures for Parkinson’s disease

Fig. 2

a The bar graphs and overlapped Venn diagram of unique identified proteins and phosphoproteins. b Cleveland Dot Plots for all quantified proteins and phosphoproteins. Both c proteomic and d phosphoproteomic data were normalized based on internal standards. Most quantified proteins and phosphoproteins had a CV of less than 20%. Normalized quantified data in the training set were then analyzed using feature selection to find potential biomarkers for PD. The box plots were derived from 21 HC, 13 NMC, 28 IPD, and 20 LRRK2 PD. For the lines in box plots: the line inside the box is the 50th percentile (median), the bottom and top of the box are the 25th and 75th percentiles, the whiskers are the 95% confidence interval, and any outliers are shown as open circles.

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