Table 1 The summary of cohort demographics and clinical characteristics for all 82 patients whose samples were used in the discovery experiment.

From: Quantitative proteomics and phosphoproteomics of urinary extracellular vesicles define putative diagnostic biosignatures for Parkinson’s disease

Demographics

Control

NMC

iPD

LRRK2 PD

Overall

Age (range; years)

69.4 (59–85)

58.5 (37–83)

66.1 (45–82)

69.7 (56–90)

66.6 (37–90)

Gender (Female/Male)

10/11

6/7

12/16

9/11

37/45

Disease duration (range; years)

N/a

N/a

0–18

1–26

0–26

MoCA

27.7 (24–30)

28.5 (27–30)

27.2 (23–30)

26.2 (8–30)

27.3 (8–30)

UPDRS-III

1.1 (0–5)

0.8 (0–3)

17.5 (5–38)

21.1 (1–53)

11.5 (0–53)

  1. The range units for age and disease duration are in years (see Supplementary Data 11 for more details). The groups include healthy individuals (control), healthy individuals with G2019S mutation in the LRRK2 gene (non-manifesting carrier/NMC), PD individuals without G2019S mutation (idiopathic PD/iPD), and PD individuals with G2019S mutation (LRRK2 PD).
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