Fig. 1: Analysis of differentially expressed genes in primary TNBC in response to ICI plus chemotherapy. | Communications Medicine

Fig. 1: Analysis of differentially expressed genes in primary TNBC in response to ICI plus chemotherapy.

From: Construction and validation of a gene expression classifier to predict immunotherapy response in primary triple-negative breast cancer

Fig. 1: Analysis of differentially expressed genes in primary TNBC in response to ICI plus chemotherapy.The alternative text for this image may have been generated using AI.

a Volcano plot representing the differential gene expression in Z-ratio (X-axis) and the t-test p-value, expressed as –log10(p-value) (Y-axis). b Heatmap representing the hierarchical clustering using all differentially expressed genes in the whole cohort and (c) in the validation cohort. Differentially expressed genes can successfully cluster responder and non-responder patients when using the whole cohort, but not in the validation cohort.

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