Table 4 Performance metrics across datasets with a model trained on the ADNI training set, using a cut-off of and Alzheimer’s disease (AD) score of 0.5 and employing inference using MC Dropout with 50 samples.
From: Identifying healthy individuals with Alzheimer’s disease neuroimaging phenotypes in the UK Biobank
Dataset | Accuracy | AUC | Sensitivity | Specificity | PPV/precision | NPV |
|---|---|---|---|---|---|---|
ADNI test set | 0.92 | 0.97 | 0.90 | 0.93 | 0.90 | 0.93 |
NACC (only AD/Control) | 0.74 | 0.79 | 0.68 | 0.78 | 0.65 | 0.80 |
NACC (AD/All) | 0.72 | 0.76 | 0.68 | 0.73 | 0.56 | 0.83 |