Table 3 Comparing guardians’ choice of different vaccines containing DTaP antigens before and after the vaccine incident.

From: Assessing the impact of the 2018 Changchun Changsheng vaccine incident on childhood vaccination in China

Vaccines containing DTaP antigens

Number of doses in schedule

Number of doses administered

Proportion of administered doses out of doses in schedule, %

Number of doses delayed

Proportion of delayed doses out of administered doses, %

Before incident

After incident

Before incident

After incident

Before incident

After incident

p-valuea

Before incident

After incident

Before incident

After incident

p-valuea

Overall 4 doses

    Total

10 155

5 145

10 032

4 863

98.79

94.52

0.000

2 547

1 484

25.39

30.52

0.000

    Trivalentb

  

8 858

4 062

87.23

78.95

0.000

2 313

1 334

26.11

32.84

0.000

    Quadrivalent/Pentavalentc

  

1 174

801

11.56

15.57

0.000

234

150

19.93

18.73

0.506

Dose 1

    Total

3 250

1 636

3 239

1 604

99.66

98.04

0.000

698

480

21.55

29.93

0.000

    Trivalent

  

2 852

1 317

87.75

80.50

0.000

639

441

22.41

33.49

0.000

    Quadrivalent/Pentavalent

  

387

287

11.91

17.54

0.000

59

39

15.25

13.59

0.546

Dose 2

    Total

2 839

1 308

2 826

1 264

99.54

96.64

0.000

360

222

12.74

17.56

0.000

    Trivalent

  

2 485

1 045

87.53

79.89

0.000

332

201

13.36

19.23

0.000

    Quadrivalent/Pentavalent

  

341

219

12.01

16.74

0.000

28

21

8.21

9.59

0.573

Dose 3

    Total

2 577

1 296

2 553

1 218

99.07

93.98

0.000

528

268

20.68

22.00

0.352

    Trivalent

  

2 260

1 031

87.70

79.55

0.000

486

248

21.50

24.05

0.103

    Quadrivalent/Pentavalent

  

293

187

11.37

14.43

0.006

42

20

14.33

10.70

0.246

Dose 4

    Total

1 489

905

1 414

777

94.96

85.86

0.000

961

514

67.96

66.15

0.387

    Trivalent

  

1 261

669

84.69

73.92

0.000

856

444

67.88

66.37

0.499

    Quadrivalent/Pentavalent

  

153

108

10.28

11.93

0.207

105

70

68.63

64.81

0.519

  1. aChi-square test comparing the proportions of administered or delayed doses before and after the vaccine incident.
  2. bTrivalent vaccine was involved in the Changchun Changsheng vaccine incident and was funded by National Immunization Programme.
  3. cQuadrivalent DTaP-Hib and pentavalent DTaP-IPV/Hib vaccines were not involved in the Changchun Changsheng vaccine incident and were self-paid vaccines outside of National Immunization Programme.