Table 4 Association between the vaccine incident and vaccination delay by multivariate logistic regressions.

From: Assessing the impact of the 2018 Changchun Changsheng vaccine incident on childhood vaccination in China

Variables

DTaP dose delayed vs not (n = 15,300)

NIP dose (except DTaP) delayed vs not (n = 42,099)

Non-NIP dose delayed vs not (n = 18,180)

OR

95% CI

OR

95% CI

OR

95% CI

Scheduled time for each dose

    Before vaccine incident

Ref.

 

Ref.

 

Ref.

 

    After vaccine incident

3.49**

(3.08, 3.96)

2.76**

(2.55, 2.99)

0.92

(0.81, 1.05)

Child’s age (years)

    < 1

Ref.

 

Ref.

 

Ref.

 

    1–2

1.25**

(1.08, 1.44)

2.71**

(2.44, 3.01)

0.78*

(0.65, 0.94)

    2–3

3.17**

(2.68, 3.74)

5.60**

(4.96, 6.33)

1.08

(0.88, 1.31)

    3–5

3.99**

(3.34, 4.78)

6.49**

(5.72, 7.37)

0.91

(0.74, 1.13)

Child’s gender

    Female

Ref.

 

Ref.

 

Ref.

 

    Male

1.15**

(1.06, 1.25)

1.07*

(1.01, 1.13)

1.22**

(1.10, 1.36)

    Only one child in a family

0.72**

(0.66, 0.79)

0.86**

(0.81, 0.92)

0.69**

(0.62, 0.78)

Guardian’s age (years)

    < 30

Ref.

 

Ref.

 

Ref.

 

    30–39

0.94

(0.85, 1.04)

0.99

(0.92, 1.07)

0.84*

(0.73, 0.97)

    40–49

0.75**

(0.62, 0.89)

0.94

(0.83, 1.06)

0.59**

(0.47, 0.74)

    ≥ 50

0.65*

(0.45, 0.92)

0.91

(0.73, 1.12)

0.56**

(0.36, 0.87)

Guardian’s relationship with the child

    Mother

Ref.

 

Ref.

 

Ref.

 

    Father

1.12

(1.00, 1.25)

1.07**

(0.99, 1.16)

1.18*

(1.01, 1.37)

    Grandparent

1.20

(0.86, 1.68)

1.02

(0.84, 1.25)

1.18

(0.77, 1.79)

Ethnic groups

    Han

Ref.

 

Ref.

 

Ref.

 

    Minorities

1.28**

(1.08, 1.53)

0.98

(0.86, 1.12)

1.21

(0.95, 1.54)

Guardian’s education level

    Elementary school or below

Ref.

 

Ref.

 

Ref.

 

    Middle school

0.95

(0.81, 1.12)

1.02

(0.91, 1.14)

0.76*

(0.61, 0.95)

    Senior high school or technical school

0.95

(0.80, 1.12)

1.00

(0.89, 1.13)

0.87

(0.69, 1.11)

    Three-year college or associate degree

0.90

(0.75, 1.09)

0.99

(0.86, 1.13)

0.70**

(0.54, 0.91)

    Bachelor’s degree or above

0.77*

(0.64, 0.94)

0.95

(0.82, 1.08)

0.58**

(0.45, 0.75)

Quintiles of per capita monthly income

    Quintile 1 (CNY 0–1000)

Ref.

 

Ref.

 

Ref.

 

    Quintile 2 (CNY 1001–1600)

0.98

(0.86, 1.12)

0.94

(0.85, 1.03)

0.77**

(0.64, 0.92)

    Quintile 3 (CNY 1601–2400

0.96

(0.84, 1.10)

0.92**

(0.84, 1.01)

0.69**

(0.58, 0.83)

    Quintile 4 (CNY 2401–3750)

0.99

(0.86, 1.14)

0.97

(0.88, 1.07)

0.67**

(0.56, 0.81)

    Quintile 5 (CNY > 3751)

0.98

(0.84, 1.15)

0.94

(0.84, 1.04)

0.53**

(0.43, 0.64)

Status of residence

    Local resident

Ref.

 

Ref.

 

Ref.

 

    Inter-city migrant

1.14*

(1.03, 1.26)

1.08*

(1.01, 1.17)

1.29**

(1.11, 1.49)

Place of residence

    Rural

Ref.

 

Ref.

 

Ref.

 

    Urban

0.99

(0.90, 1.09)

1.11**

(1.03, 1.18)

0.60**

(0.53, 0.68)

Province

    Shandong

Ref.

 

Ref.

 

Ref.

 

    Beijing

0.80*

(0.67, 0.97)

0.76**

(0.68, 0.86)

6.55**

(4.55, 9.45)

    Chongqing

1.07

(0.89, 1.29)

1.72**

(1.53, 1.93)

0.80

(0.64, 1.00)

    Gansu

1.17

(0.96, 1.43)

0.77**

(0.67, 0.89)

2.28**

(1.64, 3.19)

    Guangdong

1.15

(0.96, 1.39)

0.96

(0.86, 1.09)

1.39**

(1.10, 1.77)

    Henan

0.79*

(0.65, 0.96)

0.81**

(0.71, 0.93)

0.32**

(0.26, 0.40)

    Jiangxi

0.79*

(0.65, 0.96)

0.90

(0.79, 1.02)

0.65**

(0.52, 0.82)

    Jilin

0.81*

(0.67, 0.98)

0.83**

(0.73, 0.93)

5.37**

(4.10, 7.03)

    Yunnan

1.14

(0.94, 1.37)

1.17*

(1.04, 1.32)

0.72**

(0.57, 0.90)

    Shanghai

0.38**

(0.31, 0.47)

0.26**

(0.22, 0.31)

0.31**

(0.25, 0.39)

  1. DTaP Diphtheria-tetanus-pertussis, NIP National Immunization Program, CNY Chinese Yuan, 1 CNY = 0.14496 USD in 2019.
  2. In the regressions, standard errors are clustered at the individual child level. OR Odds ratio, CI Confidence interval. **p < 0.01, *p < 0.05.
Back to article page