Table 1 Baseline demographics and clinical characteristics of the 4 cohorts included in the study.
Characteristics | Cohort 1 | Cohort 2 | Cohort 3 | Cohort 4 | ||||
|---|---|---|---|---|---|---|---|---|
PI Cases (n = 797) | Controls (n = 797) | PI Cases (n = 797) | Controls (n = 797) | PI Cases (n = 2312) | Controls (n = 2312) | PI Cases (n = 19,924) | Controls (n = 19,924) | |
Age and Gender | ||||||||
Age (years) | 46 ± 26 | 46 ± 25 | 46 ± 26 | 48 ± 24 | 44 ± 26 | 45 ± 24 | 47 ± 24 | 46 ± 23 |
18–30 (%) | 16.39 | 16.32 | 16.98 | 17.02 | 17.12 | 17.14 | 13.89 | 14.01 |
31–50 (%) | 24.55 | 24.61 | 23.96 | 23.91 | 23.65 | 23.69 | 28.98 | 29.79 |
51–70 (%) | 35.85 | 35.79 | 36.05 | 35.85 | 34.81 | 34.79 | 35.76 | 36.03 |
71-max age (%) | 23.21 | 23.28 | 23.01 | 23.22 | 24.43 | 24.38 | 21.37 | 20.17 |
Male (%) | 46.9 | 46.3 | 46.6 | 45.4 | 44.3 | 41.7 | 38.7 | 37.8 |
Female (%) | 53.1 | 53.7 | 53.4 | 54.6 | 55.7 | 58.3 | 61.3 | 62.2 |
Ethnicity (%) | ||||||||
Caucasian | 82.4 | 85.1 | 83.4 | 88.1 | 81.7 | 84.2 | 85.3 | 86.8 |
African American | 8.7 | 7.3 | 8.4 | 6.7 | 7.9 | 7.2 | 5.8 | 5.8 |
Asian | 1.4 | 1.5 | 1.3 | 0.5 | 1.7 | 1.6 | 1.2 | 1.1 |
Other/Unknown | 7.5 | 6.1 | 7 | 4.7 | 8.7 | 7.1 | 7.8 | 6.3 |
Patient History | ||||||||
Diagnosis History duration (years)a | 10 (8–13) | 12 (10–14) | 10 (8–13) | 12 (9–14) | 9 (6–12) | 11 (8–14) | 9 (6–12) | 11 (8–14) |
Number of visitsa | 201 (103–399) | 145 (48–415) | 206 (105–399) | 182 (45–397) | 108 (36–250) | 73 (17–243.5) | 87 (30–206) | 64 (16–195) |
