Table 1 The Meso Scale Discovery (MSD) panels comprising the MSD V-PLEX Human Biomarker 54-plex kit and their biomarkers
MSD panel (all human) | Measured at | Dilution factor | Biomarkers |
|---|---|---|---|
Proinflammatory Panel 1 | RH | 1:2 | IFN-γ, IL-1β, IL-2, IL-4, IL-6, CXCL8/IL-8, IL-10, IL-12p70, IL-13, TNF-α |
Cytokine Panel 1 | RH | 1:2 | GM-CSF, IL-1α, IL-5, IL-7, IL-12/IL-23p40, IL-15, IL-16, IL-17A, TNF-β, VEGF-A |
Cytokine Panel 2 | DTU | 1:4 | IL-17A/F, IL-17B, IL-17C, IL-17D, IL-1RA, IL-3, IL-9, TSLP |
TH17 Panel 1 (excluded) | AUH | 1:4 | IL-17A (Gen.B) IL-21, IL-31, IL-27, IL-23, IL-22, MIP-3α |
Angiogenesis Panel 1 | AUH | 1:2 | FGF (basic), VEGFR-1/Flt-1, PlGF, Tie-2, VEGF-A, VEGF-C, VEGF-D |
Chemokine Panel 1 | DTU | 1:4 | CCL11 (Eotaxin), CCL4 (MIP-1β), CCL26 (Eotaxin-3), CCL17 (TARC), CXCL10 (IP-10), CCL3 (MIP-1α), CXCL8/IL-8, CCL2 (MCP-1), CCL22 (MDC), CCL13 (MCP-4) |
Vascular Injury Panel 2 | DTU | 1:1000 | SAA, CRP, sVCAM-1, sICAM-1 |
