Table 3 Significance and fold change for LPC(26:0), total C26:0 and LPC(32:0) for defined patient group comparisons

From: Lipidomic biomarkers in plasma correlate with disease severity in adrenoleukodystrophy

 

LPC(26:0)

C26:0

LPC(32:0)

 

p

FC

p

FC

pa

FC

CALD vs NoCALD (all ages)

0.0001907

1.52

0.0067250

1.21

0.0000005

2.19

CALD vs NoCALD >55

0.0000010

2.24

0.0002741

1.45

0.0000003

3.74

AI vs NoAI (all ages)

0.0000069

1.58

0.0106273

1.16

0.0000022

2.15

AI vs NoAI >55

0.0000014

2.01

0.0008446

1.33

0.0000008

3.13

severe vs mild (male)

0.0005898

1.82

0.0013877

1.4

0.0007270

2.58

severe vs mild (female)

0.0076843

1.43

0.0064491

1.26

na

na

  1. aUnadjusted p-value.
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