Fig. 4: Congo red detection of amyloid-like proteins.
From: Biomarkers and point of care screening approaches for the management of preeclampsia
The congo red paper test can detect amyloid-like proteins in the urine of pregnant women, via congophilia123,141. Specifically, excess amyloid-like proteins promote the intercalation of congo red, reducing the availability and subsequent binding of the dye on the cellulose fibers. The size and distribution of the red spot is used to estimate the concentration of misfolded proteins. The lower left image shows the actual assay. The lower right image shows an example of actual test results and their interpretation.
