Table 3 Distribution of polymyxin resistance-related gene mutations in polymyxin-resistant CRKP strains

From: Increasing polymyxin resistance in clinical carbapenem-resistant Klebsiella pneumoniae strains in China between 2000 and 2023

Gene

Mutations (n)

mgrB

ISKpn26 insertion (20); IS903B insertion (14); ISKpn14 insertion (9);

ISKpn18 insertion (1); mgrB truncated (7); Complete deletion (5);

K3* (2); C39G (1);

pmrA

G53C (1); G53V (1);

pmrB

T157P (3); S85R (2);

phoP

E82K (1); Y98C (1);

phoQ

L62P (2); L247P (2);

crrA

/

crrB

/