Table 3 Simulated excess isolation burden under different isolation guidelinesa

From: Age- and vaccination status-dependent isolation guidelines based on simulation of SARS-CoV-2 Delta cases in Singapore

Criteria of acceptable leaking risk/ \({R}_{e}\)

Isolation guidelines

Length of isolation (days)

Excess isolation burden (days)

Leaking risk <10%

Fixed-period

14

7.4

Variable-period (vaccination status)

17 (unvaccinated)

9 (vaccinated)

6.4

Variable-period (vaccination status, age)

16 (unvaccinated, <60)

14 (unvaccinated, >60)

10 (vaccinated, <60)

9 (vaccinated, >60)

6.0

\({R}_{e} < 1\)

Fixed-period

11

4.4

Variable-period

13 (unvaccinated)

6 (vaccinated)

2.9

Variable-period (vaccination status, age)

12 (unvaccinated, <60)

13 (unvaccinated, >60)

6 (vaccinated, <60)

7 (vaccinated, >60)

2.6

  1. aThe infectiousness threshold was set as Ct = 25 (106.11 copies/mL).
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