Table 1 Total post-vaccine response following 104 vaccines as determined by the Area Under the MCIR curve based on vaccine dose, vaccine type, sex and age
Demographic and vaccine categories | n (%) with a detectablea response | Median (IQR) area under the MCIR curve | p-valueb of comparison of area under the MCIR curve | |
|---|---|---|---|---|
Vaccine Dose | 1st Dose (n = 15) | 8 (53.3) | 0.043 (0.04) | 1st vs 2nd dose: p = 0.01 1st vs 3rd dose: p = 0.06 2nd vs 3rd dose: p = 0.41 |
2nd Dose (n = 44) | 31 (70.5) | 0.083 (0.18) | ||
3rd Dose (n = 45) | 27 (60.0) | 0.063 (0.13) | ||
Vaccine Typec | mRNA-1273 (n = 36) | 26 (72.2) | 0.116 (0.19) | p = 0.06 |
BNT162b2 (n = 41) | 24 (58.5) | 0.055 (0.096) | ||
Sexc | Females (n = 41) | 25 (61.0) | 0.070 (0.15) | p = 0.60 |
Males (n = 48) | 33 (68.8) | 0.065 (0.14) | ||
Age by Tertilec | Lowest Tertile Age (range 19–28) (n = 31) | 21 (67.7) | 0.070 (0.13) | Lowest vs Middle Tertile: p = 0.99 Middle vs Highest Tertile: p = 0.13 Lowest vs Highest Tertile: p = 0.08 |
Middle Tertile Age (range 28–45.8) (n = 26) | 20 (76.9) | 0.056 (0.12) | ||
Highest Tertile Age (range 45.8–69) (n = 29) | 16 (55.2) | 0.077 (0.20) |
