Fig. 5: Impact of different types of combined oral contraceptives (COCs) on the plasma proteome in CHRIS. | Communications Medicine

Fig. 5: Impact of different types of combined oral contraceptives (COCs) on the plasma proteome in CHRIS.

From: Extensive modulation of the circulating blood proteome by hormonal contraceptive use across two population studies

Fig. 5

COCs with ethinylestradiol induce more pronounced changes in protein abundances compared to those containing bioidentical estrogen, whereas those containing progesterone affect a different set of plasma proteins. a Effect sizes for COCs with ethinylestradiol (n = 248) against effect sizes for COCs with bioidentical estrogen (n = 17). b Effect sizes of COCs with ethinylestradiol against those for progesterone preparations (n = 6). Each point represents data from one protein. Solid black lines represent the linear regression fit to the data points with its slope and p-value shown in the top left corner.

Back to article page