Table 1 Numbers and types of adverse events occurring during the study
From: Rapamycin treatment for Alzheimer’s disease and related dementias: a pilot phase 1 clinical trial
Adverse event (N = 20) | Total N (N before Txt) | Severity (N before Txt) | Relatedness (N before Txt) |
|---|---|---|---|
Skin | |||
Rash | 1 (0) | Mild | Unlikely |
Infection | 2 (1) | Mild (moderate) | Unlikely (not related) |
Gastrointestinal | |||
Diarrhea | 2 (1) | Mild (mild) | Possible (not related) |
Emesis | 2 (1) | Mild (mild) | Unlikely (not related) |
Respiratory | |||
Cough | 2 (0) | Mild | Unlikely |
Infection | 1 (0) | Mild | Unlikely |
Genitourinary | |||
Urinary urgency | 1 (0) | Mild | Possible |
Urinary incontinence | 1 (0) | Mild | Unlikely |
Urinary retention | 1 (0) | Mild | Not related |
General | |||
Leg edema | 2 (0) | Mild/moderate | Not related/unlikely |
Fall | 2 (1) | Mild (mild) | Not related (not related) |
Nervous system | |||
Headache | 1 (1) | (Moderate) | (Unlikely) |
Suspected TIA | 1 (1) | (Severe) | (Not related) |
Metabolism | |||
Hypokalemia | 1 (0) | Mild | Not related |
