Table 1 Characteristics of MMD in the derivation and validation cohorts
Variable | Derivation Cohort (Patients) (N = 1980) | Derivation Cohort (Hemispheres) (N = 3692) | Validation Cohort (Patients) (N = 1012) | Validation Cohort (Hemispheres) (N = 1833) |
|---|---|---|---|---|
Sex (female: male) | 1.23 | 1.25 | 1.14 | 1.16 |
Postoperative Infarction | 131 (6.62%) | 146 (3.95%) | 91 (8.99%) | 97 (5.29%) |
Age, median (IQR), (years) | 41.00 (33.09–48.00) | 41.00 (33.10–48.02) | 45.54 (36.90–52.46) | 45.53 (36.93–52.33) |
Hypertension | 668 (33.74%) | 1251 (33.88%) | 414 (40.91%) | 747 (40.75%) |
Hyperlipidaemia | 95 (4.80%) | 175 (4.74%) | 127 (12.55%) | 236 (12.87%) |
Diabetes | 201 (10.15%) | 380 (10.29%) | 133 (13.14%) | 242 (13.20%) |
Immune disease | 14 (0.71%) | 23 (0.62%) | 8 (0.79%) | 14 (0.76%) |
Coronary heart disease | 6 (0.30%) | 10 (0.33%) | 31 (3.06%) | 57 (3.11%) |
Hyperthyroidism | 36 (1.82%) | 71 (1.92%) | 20 (1.98%) | 38 (2.07%) |
Hypothyroidism | 10 (0.51%) | 20 (0.54%) | 13 (1.28%) | 25 (1.36%) |
Smoke | 217 (10.96%) | 398 (10.78%) | 174 (17.19%) | 311 (16.97%) |
Alcohol | 132 (6.67%) | 243 (6.58%) | 97 (9.58%) | 171 (9.33%) |
Ischaemic stroke history | 933 (47.12%) | 1753 (47.48%) | 445 (43.97%) | 817 (44.57%) |
Haemorrhagic stroke history | 610 (30.81%) | 1120 (30.34%) | 250 (24.70%) | 452 (24.66%) |
Revascularization | ||||
Combined | 1180 (59.60%) | NA | 732 (72.33%) | NA |
Indirect | 800 (40.40%) | NA | 280 (27.67%) | NA |
DSA | ||||
Suzuki Stage | ||||
I | NA | 311 (8.42%) | NA | 167 (9.11%) |
II | NA | 832 (22.54%) | NA | 469 (25.59%) |
III | NA | 512 (13.87%) | NA | 339 (18.49%) |
IV | NA | 577 (15.63%) | NA | 246 (13.42%) |
V | NA | 654 (17.71%) | NA | 203 (11.07%) |
VI | NA | 806 (21.83%) | NA | 409 (22.31%) |
ICA stenosis in long segments | NA | 82 (2.22%) | NA | 55 (3.00%) |
ACA proximal localised stenosis | NA | 115 (3.11%) | NA | 68 (3.71%) |
Steal phenomenon | NA | 30 (0.81%) | NA | 16 (0.87%) |
PCA occlusion | NA | 98 (2.65%) | NA | 52 (2.84%) |
PCA proximal localised stenosis | NA | 46 (1.25%) | NA | 22 (1.20%) |
Poor bidirectional compensation | NA | 249 (6.74%) | NA | 100 (5.46%) |
MCA localised stenosis | NA | 189 (5.12%) | NA | 92 (5.02%) |
