Fig. 7: Classification of outcomes based on genotype and treatment. | Communications Medicine

Fig. 7: Classification of outcomes based on genotype and treatment.

From: Protection against APOE4-associated phenotypes with the longevity-promoting intervention 17α-estradiol in middle-aged male mice

Fig. 7: Classification of outcomes based on genotype and treatment.

Outcomes are categorized into five groups: (i) significant genotype differences with no significant effects of 17α-estradiol (17αE2) treatment, (ii) outcomes improved by 17αE2 treatment in both APOE3 and APOE4 mice, (iii) outcomes changed by 17αE2 treatment only or more strongly in APOE4 mice, (iv) outcomes changed by 17αE2 treatment only or more strongly in APOE3 mice, and (v) outcomes with no significant genotype or treatment effects.

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