Table 1 Demographic breakdown of study cohort
Characteristic | Total PBHS N = 2502 | Evaluable, N = 1915 | Evaluated with proteomics at start, n = 738 | |||||
|---|---|---|---|---|---|---|---|---|
Normoglycemic n = 1319 | Prediabetes n = 335 | T2D n = 263 | Normoglycemic n = 473 | Prediabetes n = 110 | T2D n = 155 | |||
Sex, n (%) | Male | 1375 (55.0) | 712 (54.0) | 182 (54.3) | 132 (50.2) | 220 (46.5) | 57 (51.8) | 81 (52.3) |
Female | 1127 (45.0) | 607 (46.0) | 153 (45.7) | 131 (49.8) | 253 (53.5) | 53 (48.2) | 74 (47.7) | |
Mean age, years (SD) | 50.0 (17.2) | 44.3 (16.5) | 59.7 (14.5) | 59.6 (12.7) | 43.6 (15.3) | 58.7 (13.6) | 58.2 (12.4) | |
Age, n (%) | 18–29 | 398 (15.9) | 319 (24.2) | 10 (3.0) | 5 (1.9) | 112 (23.7) | 1 (0.9) | 4 (2.6) |
30–39 | 451 (18.0) | 317 (24.0) | 28 (8.4) | 18 (6.8) | 110 (23.3) | 11 (10.0) | 10 (6.5) | |
40–49 | 411 (16.4) | 232 (17.6) | 42 (12.5) | 40 (15.2) | 93 (19.7) | 17 (15.5) | 28 (18.1) | |
50–59 | 442 (17.7) | 186 (14.1) | 75 (22.4) | 60 (22.8) | 76 (16.1) | 25 (22.7) | 36 (23.2) | |
60–69 | 399 (15.9) | 145 (11.0) | 77 (23.0) | 76 (28.9) | 55 (11.6) | 28 (25.5) | 49 (31.6) | |
70+ | 401 (16.0) | 120 (9.1) | 103 (30.7) | 64 (24.3) | 27 (5.7) | 28 (25.5) | 28 (18.1) | |
Race, n (%) | White | 1590 (63.5) | 883 (66.9) | 200 (59.7) | 148 (56.3) | 310 (65.5) | 64 (58.2) | 87 (56.1) |
Black/African American | 400 (16.0) | 138 (10.5) | 78 (23.3) | 77 (29.3) | 59 (12.5) | 28 (25.5) | 47 (30.3) | |
Asian | 272 (10.9) | 147 (11.1) | 38 (11.3) | 22 (8.4) | 58 (12.3) | 12 (10.9) | 12 (7.7) | |
Hispanic | 88 (3.5) | 54 (4.1) | 9 (2.7) | 7 (2.7) | 12 (2.5) | 4 (3.6) | 3 (1.9) | |
Mixed | 70 (2.8) | 45 (3.4) | 4 (1.2) | 3 (1.1) | 16 (3.4) | 1 (0.9) | 2 (1.3) | |
American Indian/Alaskan | 31 (1.2) | 21 (1.6) | 2 (0.6) | 1 (0.4) | 6 (1.3) | 1 (0.9) | 0 | |
Hawaiian/Pacific Islander | 28 (1.1) | 14 (1.1) | 3 (0.9) | 3 (1.1) | 9 (1.9) | 0 | 2 (1.3) | |
Other | 23 (0.9) | 17 (1.3) | 1 (0.3) | 2 (0.8) | 3 (0.6) | 0 | 2 (1.3) | |
RBG, mean (SD) | 97.7 (36.3) | 87.4 (11.2) | 93.8 (13.8) | 150.3 (70.0) | 88.0 (12.8) | 95.7 (15.0) | 153.0 (68.8) | |
HbA1c, mean (SD) | 5.7 (1.0) | 5.2 (0.3) | 5.9 (0.2) | 7.5 (1.8) | 5.2 (0.3) | 5.9 (0.3) | 7.4 (1.7) | |
BMI, mean (SD) | 28.4 (6.8) | 26.8 (5.8) | 29.2 (6.5) | 34.3 (7.9) | 27.2 (6.0) | 30.7 (6.5) | 34.6 (7.4) | |
Comorbidities, n (%) | 988 (39.5) | 498 (37.8) | 145 (43.3) | 104 (39.5) | 171 (36.2) | 39 (35.5) | 39 (25.2) | |
Hypertension, n (%) | 682 (27.3) | 194 (14.7) | 122 (36.4) | 164 (62.4) | 76 (16.1) | 49 (44.5) | 101 (65.2) | |
Hypertension medication, n (%) | 596 (23.8) | 146 (11.1) | 106 (31.6) | 164 (62.4) | 56 (11.8) | 40 (36.4) | 99 (63.9) | |
Statins, n (%) | 418 (16.7) | 90 (6.8) | 92 (27.5) | 124 (47.1) | 35 (7.4) | 38 (34.5) | 69 (44.5) | |