Table 1 Demographic breakdown of study cohort

From: Multi-modal analyses of proteomic measurements associated with type 2 diabetes from the Project Baseline Health Study

Characteristic

Total PBHS

N = 2502

Evaluable, N = 1915

Evaluated with proteomics at start, n = 738

Normoglycemic

n = 1319

Prediabetes

n = 335

T2D

n = 263

Normoglycemic

n = 473

Prediabetes

n = 110

T2D

n = 155

Sex,

n (%)

Male

1375 (55.0)

712 (54.0)

182 (54.3)

132 (50.2)

220 (46.5)

57 (51.8)

81 (52.3)

Female

1127 (45.0)

607 (46.0)

153 (45.7)

131 (49.8)

253 (53.5)

53 (48.2)

74 (47.7)

Mean age, years (SD)

50.0 (17.2)

44.3 (16.5)

59.7 (14.5)

59.6 (12.7)

43.6 (15.3)

58.7 (13.6)

58.2 (12.4)

Age,

n (%)

18–29

398 (15.9)

319 (24.2)

10 (3.0)

5 (1.9)

112 (23.7)

1 (0.9)

4 (2.6)

30–39

451 (18.0)

317 (24.0)

28 (8.4)

18 (6.8)

110 (23.3)

11 (10.0)

10 (6.5)

40–49

411 (16.4)

232 (17.6)

42 (12.5)

40 (15.2)

93 (19.7)

17 (15.5)

28 (18.1)

50–59

442 (17.7)

186 (14.1)

75 (22.4)

60 (22.8)

76 (16.1)

25 (22.7)

36 (23.2)

60–69

399 (15.9)

145 (11.0)

77 (23.0)

76 (28.9)

55 (11.6)

28 (25.5)

49 (31.6)

70+

401 (16.0)

120 (9.1)

103 (30.7)

64 (24.3)

27 (5.7)

28 (25.5)

28 (18.1)

Race, n (%)

White

1590 (63.5)

883 (66.9)

200 (59.7)

148 (56.3)

310 (65.5)

64 (58.2)

87 (56.1)

Black/African American

400 (16.0)

138 (10.5)

78 (23.3)

77 (29.3)

59 (12.5)

28 (25.5)

47 (30.3)

Asian

272 (10.9)

147 (11.1)

38 (11.3)

22 (8.4)

58 (12.3)

12 (10.9)

12 (7.7)

Hispanic

88 (3.5)

54 (4.1)

9 (2.7)

7 (2.7)

12 (2.5)

4 (3.6)

3 (1.9)

Mixed

70 (2.8)

45 (3.4)

4 (1.2)

3 (1.1)

16 (3.4)

1 (0.9)

2 (1.3)

American Indian/Alaskan

31 (1.2)

21 (1.6)

2 (0.6)

1 (0.4)

6 (1.3)

1 (0.9)

0

Hawaiian/Pacific Islander

28 (1.1)

14 (1.1)

3 (0.9)

3 (1.1)

9 (1.9)

0

2 (1.3)

Other

23 (0.9)

17 (1.3)

1 (0.3)

2 (0.8)

3 (0.6)

0

2 (1.3)

RBG, mean (SD)

97.7 (36.3)

87.4 (11.2)

93.8 (13.8)

150.3 (70.0)

88.0 (12.8)

95.7 (15.0)

153.0 (68.8)

HbA1c, mean (SD)

5.7 (1.0)

5.2 (0.3)

5.9 (0.2)

7.5 (1.8)

5.2 (0.3)

5.9 (0.3)

7.4 (1.7)

BMI, mean (SD)

28.4 (6.8)

26.8 (5.8)

29.2 (6.5)

34.3 (7.9)

27.2 (6.0)

30.7 (6.5)

34.6 (7.4)

Comorbidities, n (%)

988 (39.5)

498 (37.8)

145 (43.3)

104 (39.5)

171 (36.2)

39 (35.5)

39 (25.2)

Hypertension, n (%)

682 (27.3)

194 (14.7)

122 (36.4)

164 (62.4)

76 (16.1)

49 (44.5)

101 (65.2)

Hypertension medication, n (%)

596 (23.8)

146 (11.1)

106 (31.6)

164 (62.4)

56 (11.8)

40 (36.4)

99 (63.9)

Statins, n (%)

418 (16.7)

90 (6.8)

92 (27.5)

124 (47.1)

35 (7.4)

38 (34.5)

69 (44.5)

  1. Summary statistics were computed for the entire PBHS cohort and for the PBHS participants with proteomic data generated from plasma collected during the initial study start visit. Clinical and medication status was evaluated at study start. Comorbidities were: cancer, autoimmune diseases, excluding diabetes, infectious diseases, diverticulitis, pancreatitis, and pneumonia.
  2. BMI body mass index, HbA1c glycated hemoglobin, RBG random blood glucose, SD standard deviation, T2D type 2 diabetes.