Fig. 3: Correlation of generated nitrite and bacterial count in routinely collected clinical urine samples of patients with and without confirmed UTI. | Communications Medicine

Fig. 3: Correlation of generated nitrite and bacterial count in routinely collected clinical urine samples of patients with and without confirmed UTI.

From: Feasibility of serial measurement of nitrite for pharmacodynamic monitoring and precision prescribing in urinary tract infections

Fig. 3: Correlation of generated nitrite and bacterial count in routinely collected clinical urine samples of patients with and without confirmed UTI.

a generated nitrite per µM creatinine for 25 patients without UTI and 25 patients with confirmed UTI. Mean values of the groups are shown as black bar, with error bars representing 95% confidence intervals. A p-value of <0.001 from a Mann-Whitey U-test indicates statistical significant difference between the groups. b generated nitrite per µM creatinine for UTI patients is correlated with bacterial count (Spearman correlation: 0.46, p-value: 0.0032), when 3 UTI samples tested false negative for nitrite (red) were excluded. The solid line in b) represents the linear least squares fit, and the shaded area indicates the 95% confidence interval around the fit.

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