Fig. 4: Identification of sex-specific diagnostic associations with delirium, including dementia subtypes and infections. | Communications Medicine

Fig. 4: Identification of sex-specific diagnostic associations with delirium, including dementia subtypes and infections.

From: Comorbidities associated with a clinically-recognized delirium diagnosis in the hospital using real world data

Fig. 4

Log–log plots comparing differential diagnoses enriched in delirium patients in UCSF (x-axis) versus UC -wide (y-axis) databases. Each dot represents a diagnosis that is significantly different between delirium versus control patients in both datasets. Axis values represent log base 2 of the odds ratio between delirium versus control patients in the UCSF dataset on the x-axis and the UC-Wide dataset on the y-axis. Plots split by diagnoses significant only in females (a), only in males (b), or in both (c). Diagnoses with largest OR values highlighted. Spearman correlation ρ = 0.9 (a), 0.35 (b), 0.55 (c). Dotted line represents perfect correlation between the magnitude of the odds ratios between the two datasets. For UCSF dataset: n = 3608 female control patients; 3637 female patients with delirium; 3836 male control patients; 3884 male patients with delirium. For UC-wide dataset: n = 8451 female control patients; 8458 female patients with delirium; 10,966 male control patients; 10,959 male patients with delirium. See also Supplementary Figs. 4 and 5 and Supplementary Data 6 and 7. OR odds ratio, UC University of California, UCSF University of California San Francisco, AD Alzheimer’s disease, C. Diff colitis Clostridioides Difficile colitis, CNS central nervous system, d/o disorder.

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