Fig. 6: In Plasmodium falciparum-infected pregnant women, opsonising antibodies against placental binding CS2-IEs correlate with protection from placental malaria.

Antibody-dependent phagocytosis (ADP) by (a) neutrophils and (b) monocytes of CS2-IEs opsonised using plasma from pregnant women diagnosed with malaria (n = 77) from Papua New Guinea is measured. Dots represent means from three experiments performed in duplicate using different whole blood donors, horizontal bars show group medians. ADP was expressed as relative phagocytosis, the percentage of the pooled immune plasma (PPS). Groups were compared using Mann Whitney-U Test. (Abbreviations: non-PM=non-placental malaria, PM=placental malaria, AU=Arbitrary Units).