Table 2 Linear regression for WMH regions associated with different cognitive domains

From: Cognitive characteristics and ischemic prognosis of quantitative white matter hyperintensities in adult moyamoya disease

Variablesa

Whole-brain WMH

PVWMH

DWMH

 

R2

P (F )

β

P

Adjusted P

R2

P (F )

β

P

Adjusted P

R2

P (F )

β

P

Adjusted P

CRT

0.071

0.013

0.002

0.985

15.760

0.044

0.088

0.080

0.360

5.760

0.077

0.009

−0.057

0.501

8.016

RAVEN

0.077

0.081

−0.130

0.265

4.240

0.081

0.069

−0.230

0.050

0.800

0.062

0.146

0.014

0.989

15.824

ROTATION

0.013

0.916

−0.112

0.499

7.984

0.033

0.725

−0.165

0.318

5.088

0.002

0.995

−0.039

0.814

13.024

SWM

0.095

0.114

−0.149

0.290

4.640

0.046

0.421

−0.106

0.463

7.408

0.125

0.047

−0.190

0.170

2.720

VWM1

0.086

0.004

−0.151

0.075

1.200

0.068

0.018

−0.185

0.031*

0.496

0.077

0.009

−0.102

0.229

3.664

VWM2

0.089

0.004

−0.156

0.066

1.056

0.076

0.010

−0.206

0.017*

0.272

0.077

0.009

−0.101

0.238

3.808

SUB

0.106

0.031

−0.172

0.122

1.952

0.064

0.154

−0.145

0.202

3.232

0.099

0.040

−0.168

0.133

2.128

COMSUB

0.083

0.072

−0.066

0.549

8.784

0.047

0.272

−0.077

0.493

7.888

0.081

0.078

−0.42

0.707

11.312

WORDM

0.082

0.007

−0.130

0.113

1.808

0.044

0.094

−0.078

0.351

5.616

0.093

0.003

−0.172

0.036*

0.576

PICTM

0.010

0.939

0.044

0.787

12.592

0.099

0.382

0.123

0.427

6.832

0.005

0.976

−0.031

0.853

13.648

EXCUT1

0.116

0.019

−0.232

0.041*

0.656

0.033

0.718

−0.138

0.398

6.368

0.106

0.029

−0.188

0.099

1.584

EXCUT2

0.094

0.012

−0.256

0.024*

0.384

0.103

0.032

−0.280

0.015*

0.240

0.107

0.028

−0.189

0.095

1.520

Number comparison

0.115

0.006

−0.074

0.445

7.120

0.071

0.058

−0.047

0.634

10.144

0.125

0.004

0.087

0.365

5.840

Visual tracing

0.107

0.010

−0.033

0.736

11.776

0.078

0.045

−0.092

0.363

5.808

0.110

0.009

0.030

0.764

12.224

Figure matching

0.120

0.005

−0.132

0.194

3.104

0.086

0.027

−0.143

0.169

2.704

0.116

0.006

−0.094

0.354

5.664

GO/NO GO

0.124

0.001

−0.200

0.032*

0.512

0.087

0.025

−0.137

0.153

2.448

0.164

0.000

−0.226

0.015*

0.240

  1. Adjusted P (Bonferroni correction) = P values × compared times (16).
  2. CRT choice reaction time RAVEN Raven’s Standard Progressive Matrices, ROTATION mental rotation, SWM spatial working memory, VWM1 verbal working memory, recite in order, VWM2 verbal working memory, recite in reverse order, SUB simple subtraction, COMSUB complex subtraction, WORDM word memory, PICTM picture memory, EXCUT1 executive function, same direction, EXCUT2 executive function, opposite direction, PVWMH periventricular white matter hyperintensity, DWMH deep white matter hyperintensity, P (F) P values with F test, β standardized coefficient.
  3. *P values <0.05.
  4. aCognitive results were adjusted for age, sex, and education years.