Table 2 Linear regression for WMH regions associated with different cognitive domains
Variablesa | Whole-brain WMH | PVWMH | DWMH | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
R2 | P (F ) | β | P | Adjusted P | R2 | P (F ) | β | P | Adjusted P | R2 | P (F ) | β | P | Adjusted P | |
CRT | 0.071 | 0.013 | 0.002 | 0.985 | 15.760 | 0.044 | 0.088 | 0.080 | 0.360 | 5.760 | 0.077 | 0.009 | −0.057 | 0.501 | 8.016 |
RAVEN | 0.077 | 0.081 | −0.130 | 0.265 | 4.240 | 0.081 | 0.069 | −0.230 | 0.050 | 0.800 | 0.062 | 0.146 | 0.014 | 0.989 | 15.824 |
ROTATION | 0.013 | 0.916 | −0.112 | 0.499 | 7.984 | 0.033 | 0.725 | −0.165 | 0.318 | 5.088 | 0.002 | 0.995 | −0.039 | 0.814 | 13.024 |
SWM | 0.095 | 0.114 | −0.149 | 0.290 | 4.640 | 0.046 | 0.421 | −0.106 | 0.463 | 7.408 | 0.125 | 0.047 | −0.190 | 0.170 | 2.720 |
VWM1 | 0.086 | 0.004 | −0.151 | 0.075 | 1.200 | 0.068 | 0.018 | −0.185 | 0.031* | 0.496 | 0.077 | 0.009 | −0.102 | 0.229 | 3.664 |
VWM2 | 0.089 | 0.004 | −0.156 | 0.066 | 1.056 | 0.076 | 0.010 | −0.206 | 0.017* | 0.272 | 0.077 | 0.009 | −0.101 | 0.238 | 3.808 |
SUB | 0.106 | 0.031 | −0.172 | 0.122 | 1.952 | 0.064 | 0.154 | −0.145 | 0.202 | 3.232 | 0.099 | 0.040 | −0.168 | 0.133 | 2.128 |
COMSUB | 0.083 | 0.072 | −0.066 | 0.549 | 8.784 | 0.047 | 0.272 | −0.077 | 0.493 | 7.888 | 0.081 | 0.078 | −0.42 | 0.707 | 11.312 |
WORDM | 0.082 | 0.007 | −0.130 | 0.113 | 1.808 | 0.044 | 0.094 | −0.078 | 0.351 | 5.616 | 0.093 | 0.003 | −0.172 | 0.036* | 0.576 |
PICTM | 0.010 | 0.939 | 0.044 | 0.787 | 12.592 | 0.099 | 0.382 | 0.123 | 0.427 | 6.832 | 0.005 | 0.976 | −0.031 | 0.853 | 13.648 |
EXCUT1 | 0.116 | 0.019 | −0.232 | 0.041* | 0.656 | 0.033 | 0.718 | −0.138 | 0.398 | 6.368 | 0.106 | 0.029 | −0.188 | 0.099 | 1.584 |
EXCUT2 | 0.094 | 0.012 | −0.256 | 0.024* | 0.384 | 0.103 | 0.032 | −0.280 | 0.015* | 0.240 | 0.107 | 0.028 | −0.189 | 0.095 | 1.520 |
Number comparison | 0.115 | 0.006 | −0.074 | 0.445 | 7.120 | 0.071 | 0.058 | −0.047 | 0.634 | 10.144 | 0.125 | 0.004 | 0.087 | 0.365 | 5.840 |
Visual tracing | 0.107 | 0.010 | −0.033 | 0.736 | 11.776 | 0.078 | 0.045 | −0.092 | 0.363 | 5.808 | 0.110 | 0.009 | 0.030 | 0.764 | 12.224 |
Figure matching | 0.120 | 0.005 | −0.132 | 0.194 | 3.104 | 0.086 | 0.027 | −0.143 | 0.169 | 2.704 | 0.116 | 0.006 | −0.094 | 0.354 | 5.664 |
GO/NO GO | 0.124 | 0.001 | −0.200 | 0.032* | 0.512 | 0.087 | 0.025 | −0.137 | 0.153 | 2.448 | 0.164 | 0.000 | −0.226 | 0.015* | 0.240 |