Table 1 Patients’ characteristics at baseline

From: Machine learning-assisted assessment of extracellular vesicles can monitor cellular rejection after heart transplant

Variable

Study cohort (n = 24)

Sex (ref. Male; n, %)

20 (83.3)

Age at transplant (years)

58 ± 12.5

Weight (kg)

74 ± 15.6

BMI (kg/m2)

24.7 ± 4.73

Systolic BP (mmHg)

119 ± 19.6

Diastolic BP (mmHg)

68 ± 12.4

Heart rate (apm)

90 ± 14.7

Creatinine (μMol/L)

121 ± 69.1

eGFR (mL/min)

65 ± 28.5

AST (U/L)

30 ± 14.7

ALT (U/L)

34 ± 27.7

LV ejection fraction (%)

63 ± 5.0

TAPSE (mm)

18 ± 3.4

sPAP (mmHg)

31 ± 8.9

Valvular diseasea (ref. Yes; n, %)

11 (54.2)

NYHA Class

 

 Class I (n, %)

23 (95.8)

 Class II (n, %)

1(4.2)

Follow-up period (days)

303 [248; 362]

Follow-up visit interval (days)

28 [14; 35]

Rejection episodes

 

 Grade 0

181 (63.5)

 Grade 1A/B

80 (28.1)

 Grade 2

10 (3.5)

 Grade 3A

14 (4.9)

  1. Patients’ characteristics at baseline (n = 24; first visit after heart transplantation); the table also shows percentage and grade of rejection episodes at follow-up (overall number of evaluations = 285).
  2. BP blood pressure, eGFR estimated glomerular filtration rate, LV left ventricular, NYHA classification New York Heart Association, sPAP systolic pulmonary artery pressure, TAPSE tricuspid annular plane systolic excursion.
  3. aAt least mild cardiac valvular disease. Parameters were indicated as mean ± standard deviation, median [and interquartile range], or absolute number (and percentage), as appropriate.
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