Fig. 4: Serum metabolomics revealed altered metabolites related to urea cycle/amino group metabolism and bile acid metabolism in subjects with PCD. | Communications Medicine

Fig. 4: Serum metabolomics revealed altered metabolites related to urea cycle/amino group metabolism and bile acid metabolism in subjects with PCD.

From: Data from multi-national aging cohorts show dysregulated metabolic pathways in people with physio-cognitive decline

Fig. 4

a Serum levels of argininosuccinic acid and creatinine involved in urea cycle/amino group metabolism in PCD relative to control. b A representation of molecules involved in urea cycle/amino group metabolism. c Serum levels of four bile acids (lithocholic acid, glycochenodeoxycholic acid, taurodeoxycholic acid, and glycocholic acid) and their precursor 7α-hydroxycholesterol in PCD versus control. d Schematic of the altered metabolites associated with bile acid metabolism. The annotated metabolites with direction of changes were indicated with colored arrows in the boxes. Metabolites shown in the outlined box without arrows denote detectable but no marked change.

Back to article page