Fig. 2: Biomarkers associated with MASLD. | Communications Medicine

Fig. 2: Biomarkers associated with MASLD.

From: Metabolomics for searching non-invasive biomarkers of metabolic dysfunction-associated steatotic liver disease in youth with vertical HIV

Fig. 2

a Receiver operating characteristic (ROC) curves of the most significant bile acid (UDCA) and first two lipids (TG54:5 and TG 56:7) in random forest analysis and plasma total triglycerides (TGs) to discriminate MASLD from the Control group. b ROC curves of binary logistic regression combining lipidic molecules. c Information on the Receiver operating characteristic (ROC) curves between MASLD and Control. d ROC curves of the two significant clinical scores for clinical steatosis detection (HSI and TyG). e ROC curves of binary logistic regression combining clinical scores and lipidic molecules. Logistic regression analyses and ROC curves were performed using IBM SPSS Software. UDCA Ursodeoxycholic acid, TGs Triglycerides, TyG Triglycerides and Glucose ratio, HSI hepatic steatosis index. MASLD ≥ indicates the cut-off value for each variable with specific specificity and sensitivity

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