Fig. 5: Iron staining of tumor specimens confirms the biological origin of PDR. | Communications Medicine

Fig. 5: Iron staining of tumor specimens confirms the biological origin of PDR.

From: Magnetic susceptibility properties of tumor-associated cells imaged by MRI reveal glioblastoma infiltration in the edema region

Fig. 5: Iron staining of tumor specimens confirms the biological origin of PDR.The alternative text for this image may have been generated using AI.

Top row (a, b, e, f): presurgical in vivo MRI; Bottom row (c, d, g, h): histochemical iron staining and ex vivo MRI of tumor specimens. For Patient 1, the hyperintense FLAIR region around the tumor (a) exhibits elevated PDR (b) (arrows). Perls’ staining for iron (c) of a tumor specimen shows high iron concentrations, where the corresponding ex vivo MRI scan presents high PDR (d) (arrows). For Patient 2, the boundaries of the tumor as delineated in the FLAIR image (e) present high PDR (f). Perls’ staining for iron of the analyzed tumor specimen shows high iron concentrations in areas (g) corresponding to high PDR observed in the ex vivo MRI scan (h).

Back to article page