Fig. 1: Histological and molecular characteristics of the tumor. | Communications Medicine

Fig. 1: Histological and molecular characteristics of the tumor.

From: Extraskeletal osteosarcoma harboring ETV6::NTRK3 fusion treated successfully with larotrectinib: a case study

Fig. 1: Histological and molecular characteristics of the tumor.The alternative text for this image may have been generated using AI.

a Overview of the core needle biopsy exhibiting different components (blue star—spindle cell tumor tissue, green star—lace-like osteoid formation, yellow star—tumor necrosis) (4× magnification); b spindle cell like tumor tissue with highly atypical tumor cells; c Pan-TRK immunohistochemistry showing focal weak to moderate positivity; d SATB2 immunohistochemistry showing strong positivity (b–d – 40× magnification); e molecular testing identified an ETV6::NTRK3 fusion (Archer).

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