Fig. 4: VEGFA activation exhibits spatial variability within the primary tumour. | Communications Medicine

Fig. 4: VEGFA activation exhibits spatial variability within the primary tumour.

From: Multi-modal omics analysis of a paediatric melanoma highlights mechanisms underlying treatment resistance

Fig. 4

a Non-hierarchical clustering of the top 0.5% differentially expressed genes within the primary tumour ROIs, calculated by standard deviation of log2(normalised counts). b Bubble plot of VEGFA gene expression (normalised counts) represented as bubble size, overlayed on top of images from GeoMx DSP. Images are numbered as in Supplementary Fig. 1a.

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