Fig. 3: Radiogenomics mapping. | Communications Medicine

Fig. 3: Radiogenomics mapping.

From: Imaging and RNA sequencing-based radiogenomic analysis of occult lymph node metastasis and survival in lung adenocarcinoma staged non-metastatic

Fig. 3

A ROC curves of the Radscore in the RGC. B, C Venn diagram showing the overlap of identified DEG from B two comparative lncRNAs and C mRNAs (LUAD tissues vs paracancer tissues, LUAD tissues of OLMN vs LUAD tissues of OLMP). D, E Heatmaps of module-trait relationships based on D lncRNA data and E mRNA data. The x axis represents Radscore and its component radiomics features, and the y axis represents co-expressed gene modules with various colors. Each cell includes the correlation coefficient R (top) and P value (bottom). R > 0 indicates positive correlation, represented by red; R < 0 indicates negative correlation, represented by blue; and a deeper color indicates greater correlation. F, G GO and KEGG enrichment analysis of green module genes. ROC receiver operating characteristic, Radscore radiomics score, RGC radiogenomic cohort, DEG differential expressed genes, LUAD lung adenocarcinoma, OLM occult lymph node metastasis negative, OLMP occult lymph node metastasis positive, para-Ca paracancer, ME module eigengene.

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