Fig. 4: Genetic associations with abdominal IDPs. | Communications Medicine

Fig. 4: Genetic associations with abdominal IDPs.

From: Cardiovascular measures from abdominal MRI provide insights into abdominal vessel genetic architecture

Fig. 4: Genetic associations with abdominal IDPs.

A Manhattan plot. Dotted line: single-trait significance threshold (5e-8). Dashed line: study-wide significance threshold (8e-9). Loci reaching study-wide significant locus is labeled with the closest gene. B Genetic correlation between IDPs and cardiovascular complex traits. CAD coronary artery disease, PP pulse pressure, SBP systolic blood pressure, DBP diastolic blood pressure. Point sizes are −log10(p) of the genetic correlation. Color is a genetic correlation. C Genetic correlation between IDPs and measures derived from CMR. SV stroke volume, ESV end systolic volume, EF ejection fraction, EDV end diastolic volume.

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