Fig. 3: Association between metabolite profiles and mental health outcomes, as well as MASLD risk.
From: Association between mental health and MASLD molecular insights through metabolomics
Utilizing Cox proportional hazards modeling to develop metabolic. The metabolites’ coefficients (weights) in the signature, associations with mental health, and subsequent MASLD risk. a Anxiety, this analysis included n = 17,596 participants with complete anxiety assessment data. b Trauma, this analysis included n = 55,012 participants with complete trauma assessment data. c Depression, this analysis included n = 30,798 participants with complete depression assessment data. d Mania, this analysis included n = 15,318 participants with complete mania assessment data. Forest plot shows the hazard ratios (HRs) and their 95% confidence intervals for the association between the mental health and incident MASLD. The vertical line of no effect (HR = 1) is indicated. The HR and their 95% CI for each metabolite are provided in the supplementary material of Fig. 3.
