Fig. 3: Comorbidities explained by the disease transcriptomic similarity network.
From: Sex-specific transcriptome similarity networks elucidate comorbidity relationships
Network of comorbidities recovered based on transcriptomic similarities. Each node represents a disease, colored based on the disease category it belongs to (ICD-10). Red, blue, and green edges represent comorbidities (retrieved by analyzing the epidemiology separately for women and men and adjusting for sex) recovered by calculating similarities at the gene expression level between diseases in the same way (separately for women and men and adjusting for sex differences). The dashed edges represent comorbidities described in women and men that are recovered by analyzing transcriptomic similarities separately for women and men. The network’s visualizations have been generated using Cytoscape software112.
