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Institutional trust and vaccination delay as key metrics for vaccination rollout success
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  • Published: 29 April 2026

Institutional trust and vaccination delay as key metrics for vaccination rollout success

  • Cyrus Lap Kwan Leung  ORCID: orcid.org/0000-0003-1998-53161,2,
  • Kin-Kit Li2,
  • Arthur Tang3,
  • Wilson Wai San Tam4,
  • Samuel Yeung Shan Wong1,
  • Wan In Wei  ORCID: orcid.org/0000-0001-8083-35281 &
  • …
  • Kin On Kwok  ORCID: orcid.org/0000-0002-2804-54331,5,6 

Communications Medicine (2026) Cite this article

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We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Epidemiology
  • Infectious diseases
  • Preventive medicine

Abstract

Background

Timely vaccination effectively reduced COVID-19 hospitalizations and mortality, yet vaccination hesitancy undermined this benefit. Understanding the factors contributing to hesitancy is critical for improving future pandemic control by identifying barriers to timely vaccination. This paper operationalizes hesitancy in terms of vaccine delay—a key public health metric that reflects changing vaccination policies and infection status, factors that can alter individuals’ eligibility, and real-world complexities like infections.

Method

Using longitudinal data from the earliest stage of the pandemic in Hong Kong, we examined how institutional trust and the 5C constructs (confidence, complacency, constraints, calculation, and collective responsibility) influenced both vaccination intention and timing.

Results

Our results show that only 34.89% and 42.97% of vaccinated participants received their first and third doses within 100 days of eligibility, respectively, despite rising uptake prior to government mandates. Confidence and vaccination intention are key predictors of delay, and higher institutional trust boosts both confidence and collective responsibility, thereby enhancing intention and reducing delays.

Conclusions

These findings underscore the importance of building institutional trust and public confidence to minimize vaccine delay, particularly among vulnerable populations. Ultimately, incorporating vaccine delay as a key metric into public health strategies can guide more effective interventions and strengthen pandemic preparedness.

Plain language summary

Vaccination against COVID-19 has prevented many hospitalizations and deaths, yet delays in getting vaccinated have limited these benefits. We examined why people in Hong Kong postponed vaccination and proposed vaccination delay as an important metric for understanding vaccine hesitancy and rollout success. Using repeated survey data collected during the pandemic, we analyzed how trust in health authorities and psychological factors—such as confidence, perceived barriers, and social responsibility—affected both vaccination intention and timing. We found that higher trust and confidence were linked to earlier vaccination. Recognizing vaccination delay as a key public health measure can help governments design strategies that build trust, encourage timely uptake, and improve preparedness for future pandemics.

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Acknowledgements

We would like to acknowledge support from the Health and Medical Research Fund (reference numbers: INF-CUHK-1, 17160302, 18170312, CID-CUHK-A, COVID1903008), General Research Fund (reference numbers: 14112818, 24104920), Wellcome Trust Fund (reference number: 200861/Z/16/Z), Group Research Scheme and Funding Allocation to Faculties by Research Committee and Inbound Mobility Scheme (OAL) of The Chinese University of Hong Kong. A.T. acknowledges the support from the RMIT Vietnam Strategic Innovation Challenge.

Author information

Authors and Affiliations

  1. JC School of Public Health and Primary Care, The Chinese University of Hong Kong, New Territories, Hong Kong

    Cyrus Lap Kwan Leung, Samuel Yeung Shan Wong, Wan In Wei & Kin On Kwok

  2. Department of Social and Behavioural Sciences, City University of Hong Kong, Kowloon, Hong Kong

    Cyrus Lap Kwan Leung & Kin-Kit Li

  3. School of Science, Engineering and Technology, RMIT University, Ho Chi Minh City, Vietnam

    Arthur Tang

  4. Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

    Wilson Wai San Tam

  5. Hong Kong Institute of Asia-Pacific Studies, The Chinese University of Hong Kong, New Territories, Hong Kong

    Kin On Kwok

  6. Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, UK

    Kin On Kwok

Authors
  1. Cyrus Lap Kwan Leung
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  2. Kin-Kit Li
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  3. Arthur Tang
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  4. Wilson Wai San Tam
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  5. Samuel Yeung Shan Wong
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  6. Wan In Wei
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  7. Kin On Kwok
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Corresponding authors

Correspondence to Wan In Wei or Kin On Kwok.

Ethics declarations

Competing interests

K.O.K. is an Editorial Board Member for Communications Medicine but was not involved in the editorial review or peer review, nor in the decision to publish this article. Other authors declare no competing interests.

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Cite this article

Leung, C.L.K., Li, KK., Tang, A. et al. Institutional trust and vaccination delay as key metrics for vaccination rollout success. Commun Med (2026). https://doi.org/10.1038/s43856-026-01597-4

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  • Received: 23 January 2025

  • Accepted: 08 April 2026

  • Published: 29 April 2026

  • DOI: https://doi.org/10.1038/s43856-026-01597-4

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