Fig. 2: Scope of 1,2-dimagnesiation of alkynes. | Nature Synthesis

Fig. 2: Scope of 1,2-dimagnesiation of alkynes.

From: Synthesis of trans-1,2-dimetalloalkenes through reductive anti-dimagnesiation and dialumination of alkynes

Fig. 2

a, Diboration of the generated 1,2-dimagnesioalkenes afforded the corresponding (E)-diborylalkenes. Isolated yields of the pure E isomers are shown. b, The generated 1,2-dimagnesioalkenes also reacted with carbonyl compounds such as paraformaldehyde with high stereoselectivity. c, Copper-catalysed reactions of the generated 1,2-dimagnesioalkenes with various electrophiles resulted in anti-difunctionalization of the starting alkynes.

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