Combined N-heterocyclic carbene and photoredox-catalysed strategies for the acylation of arenes offer regiocontrol that is complementary to Lewis-acid-mediated Friedel–Crafts approaches.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout

Change history
30 October 2023
A Correction to this paper has been published: https://doi.org/10.1038/s44160-023-00435-y
References
Sinha, S. K. et al. Chem. Rev. 122, 5682–5841 (2022).
Goto, Y., Sano, M., Sumida, Y. & Ohmiya, H. Nat. Synth. https://doi.org/10.1038/s44160-023-00378-4 (2023).
Reimler, J., Yu, X.-Y., Spreckelmeyer, N., Daniliuc, C. G. & Studer, A. Angew. Chem. Int. Ed. 62, e202303222 (2023).
Liu, K., Schwenzer, M. & Studer, A. ACS Catal. 12, 11984–11999 (2022).
Guin, J., Sarkar, S. D., Grimme, S. & Studer, A. Angew. Chem. Int. Ed. 47, 8727–8730 (2008).
Ishii, T., Kakeno, Y., Nagao, K. & Ohmiya, H. J. Am. Chem. Soc. 141, 3854–3858 (2019).
Han, Y.-F. et al. Nat. Commun. 13, 5574 (2022).
Bay, A. V., Fitzpatrick, K. P., Betori, R. C. & Scheidt, K. A. Angew. Chem. Int. Ed. 59, 9143–9148 (2020).
Meng, Q.-Y., Döben, N. & Studer, A. Angew. Chem. Int. Ed. 59, 19956–19960 (2020).
Ren, S.-C. et al. ACS Catal. 11, 2925–2934 (2021).
Leifert, D. & Studer, A. Angew. Chem. Int. Ed. 59, 74–108 (2020).
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Competing interests
The authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Song, R., Ren, S. & Chi, Y.R. Carbene- and photocatalysis redefine arene acylation. Nat. Synth 2, 1009–1011 (2023). https://doi.org/10.1038/s44160-023-00400-9
Published:
Version of record:
Issue date:
DOI: https://doi.org/10.1038/s44160-023-00400-9